What are the causes of sarcoidosis?
The research to reveal the exact cause of sarcoidosis is unknown. Certain inherited genes make it more likely for a person to develop sarcoidosis.
- A person with a close blood relative who has sarcoidosis is nearly 5 times as likely to develop the condition.
- The disease can appear suddenly and then disappear, or it can develop gradually and produce symptoms that come and go for a lifetime.
- Sarcoidosis may be an abnormal response to a germ by the body.
Sarcoidosis is a result of an abnormal immune system, where the body starts to attack its own tissues and organs. The resulting swelling then causes granulomas to develop in the organs. Some possible triggers include:
- Environmental factor or allergies
- Exposure to virus, fungi, or bacteria
- Exposure to chemicals
- Patients who had recent organ transplantation
- It is most common among adults between the ages of 20 and 40
- The disease is slightly more common in women than in men.
- The disease is 10 to 17 times more common in African-Americans than in Caucasians. People of Scandinavian, German, Irish, or Puerto Rican origin are also more prone to the disease.
The condition is not infectious, so it cannot be passed from person to person.
What is sarcoidosis?
Sarcoidosis is a rare condition that causes small patches of red and swollen tissue (granulomas) to develop in the organs of the body. It usually affects the lungs and skin. This condition may change the normal structure and possibly the function of an affected organ. The symptoms of sarcoidosis include:
- Reddish tender bumps or patches on the skin.
- Red and teary eyes or blurred vision.
- Swollen and painful joints.
- Enlarged and tender lymph glands in the neck, armpits, and groin.
- Enlarged lymph glands in the chest and around the lungs.
- Hoarse voice.
- Pain in the hands, feet, or other bony areas due to the formation of cysts (an abnormal sac-like growth) in bones.
- Weakness
- Weight loss
- Dry cough and shortness of breath
- Kidney stone formation.
- Enlarged liver.
- Development of abnormal or missed heartbeats (arrhythmias), inflammation of the covering of the heart (pericarditis), or heart failure.
- Nervous system effects, including hearing loss, meningitis, seizures, or psychiatric disorders (for example, dementia, depression, psychosis).
SLIDESHOW
See SlideshowCan sarcoidosis be treated?
There is no cure for sarcoidosis, but the disease may get better on its own over time. Sarcoidosis symptoms will often get better without treatment. Treatment is aimed at maintaining good lung function, reducing symptoms, and preventing organ damage.
- Corticosteroids: The most common corticosteroid prescribed for sarcoidosis is prednisone. This may reduce inflammation and slow the growth of the granulomas.
- Methotrexate: This medicine may be given to people who cannot take corticosteroids. It also may be used with corticosteroids if needed.
- Azathioprine, hydroxychloroquine, chlorambucil, cyclophosphamide, and pentoxifylline are other drugs that may be used if corticosteroids and methotrexate are not effective.
- Thalidomide and minocycline have been used in some cases of skin sarcoidosis.
- Infliximab is a new treatment that has proved useful for chronic sarcoidosis but is currently a drug to use only when standard treatments have failed.
Medicines commonly used to treat sarcoidosis may cause side effects. Side effects range from those that are mild, to those that are severe and potentially dangerous. Hence medical attention is constantly required.
Apart from the above medication patient may be required to follow lifestyle modifications which include:
- Eating a well-balanced diet with a variety of fresh fruits and vegetables
- Drinking enough fluids every day
- Getting six to eight hours of sleep each night
- Exercising regularly and managing your weight
- Quitting smoking
- Avoiding exposure to dust, chemicals, fumes, gases, toxic inhalants, and other substances that can harm your lungs
- Avoiding excessive amounts of calcium-rich foods (such as dairy products, oranges, and canned salmon with bones), vitamin D, and sunlight.
(https://www.webmd.com/lung/arthritis-sarcoidosis)
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Common Medical Abbreviations & Terms
Doctors, pharmacists, and other health-care professionals use abbreviations, acronyms, and other terminology for instructions and information in regard to a patient's health condition, prescription drugs they are to take, or medical procedures that have been ordered. There is no approved this list of common medical abbreviations, acronyms, and terminology used by doctors and other health- care professionals. You can use this list of medical abbreviations and acronyms written by our doctors the next time you can't understand what is on your prescription package, blood test results, or medical procedure orders. Examples include:
- ANED: Alive no evidence of disease. The patient arrived in the ER alive with no evidence of disease.
- ARF: Acute renal (kidney) failure
- cap: Capsule.
- CPAP: Continuous positive airway pressure. A treatment for sleep apnea.
- DJD: Degenerative joint disease. Another term for osteoarthritis.
- DM: Diabetes mellitus. Type 1 and type 2 diabetes
- HA: Headache
- IBD: Inflammatory bowel disease. A name for two disorders of the gastrointestinal (BI) tract, Crohn's disease and ulcerative colitis
- JT: Joint
- N/V: Nausea or vomiting.
- p.o.: By mouth. From the Latin terminology per os.
- q.i.d.: Four times daily. As in taking a medicine four times daily.
- RA: Rheumatoid arthritis
- SOB: Shortness of breath.
- T: Temperature. Temperature is recorded as part of the physical examination. It is one of the "vital signs."
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Sarcoidosis, a disease resulting from chronic inflammation, causes small lumps (granulomas) to develop in a wide range of body tissues and can appear in almost any body organ. However, sarcoidosis most often starts in the lungs or lymph nodes.What Causes SIADH?
SIADH is the syndrome of inappropriate antidiuretic hormone secretion. Several conditions can trigger abnormal ADH production, including infections, brain inflammation, hereditary factors, certain medications, asthma and other factors.